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Semax 30mg | Focus & Mental Clarity Research Peptide
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Semax 30mg | Focus & Mental Clarity Research Peptide

Semax (Heptapeptide / ACTH(4-10) analogue) is lyophilized synthetic peptide used as a tool compound for research into cognitive focus, memory retention, mental clarity and neuroprotective markers.

Original price was: $120.00.Current price is: $100.00.

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Suggested protocol
  • Timing: AM / focus days
  • Cycle: 10-30 days ON / 1-2 months OFF
  • Goal: Focus, memory, mental clarity

High
Purity

CoA
Available

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Shipping

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Ordering

Semax is a synthetic heptapeptide analogue of the ACTH(4-10) fragment (Met-Glu-His-Phe-Pro-Gly-Pro), originally developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. As a tool compound, Semax is used in laboratory investigations into cognitive focus, memory retention and mental clarity markers, examining how ACTH(4-10) related signaling may influence neurotrophic factor expression, dopaminergic tone and neuroprotective pathways at a cellular level. BPeptide’s Semax 30mg is supplied as a lyophilized powder, verified for identity and purity by independent third party analy

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Focus & Attention Research

Used to investigate cellular signaling pathways related to attentional control, cognitive focus and task oriented mental performance markers in controlled laboratory settings.

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Memory Retention Studies

Studied for its potential role in supporting memory formation and retention markers, with preclinical data suggesting involvement in hippocampal BDNF expression.

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Neuroprotective Pathway Research

Semax’s ACTH(4-10) scaffold provides a well-characterized molecular basis for studying neuroprotective signaling and oxidative stress resistance in neuronal cell models.

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Stable Lyophilized Format

Supplied as lyophilized powder for extended shelf stability, supporting reproducible assay conditions across longitudinal cognitive research protocols.

Product Name
Semax (ACTH(4-10) Heptapeptide Analogue)
CAS Number
80714-61-0
Sequence
Met-Glu-His-Phe-Pro-Gly-Pro
Molecular Formula
C₃₇H₅₁N₉O₁₀S
Molecular Weight
~813.9 g/mol
Quantity
130mg lyophilized powder
SKU
SEMAX30
Appearance
White to off white lyophilized powder
Solubility
Water soluble at research relevant concentrations
Storage (lyophilized)
2-8°C (36-46°F), cool and dark, protected from moisture and light
Certificate of Analysis
Available on request
Category
Brain & Focus

Standard Reconstitution Protocol

  1. Allow the vial to reach room temperature before opening.
  2. Wipe the rubber stopper with 70% isopropyl alcohol.
  3. Using a sterile syringe, add 1.0-2.0ml of bacteriostatic or sterile water slowly down the inner wall of the vial so do not inject directly onto the powder.
  4. Gently swirl until fully dissolved. Do not shake or vortex because this can denature the molecule.
  5. Label the vial with date of reconstitution.
  6. Store refrigerated at 2-8°C (36-46°F), protected from light. Do not freeze reconstituted solution, as ice crystal formation will cause structural damage to the peptide.
Reconstitution solvent Bacteriostatic water (preferred) or sterile water
Recommended volume 1.0-2.0ml per 30mg vial
Storage after reconstitution 2-8°C (36–46°F), in dark, upright
Freeze thaw cycles Avoid; do not freeze reconstituted solution
Suggested cycle 10-30 days ON / 1-2 months OFF
Maintenance cycle Repeat every 3-6 months for longitudinal cognitive focus and memory retention tracking

What is Semax used for in research?

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Semax is a synthetic heptapeptide analogue of the ACTH(4-10) fragment, originally developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. In research contexts, it is studied for its effects on focus, attention, memory retention and mental clarity markers. Research has also examined its role in BDNF upregulation, neuroprotection and modulation of dopaminergic and serotonergic pathways in preclinical models.

How do you reconstitute Semax 30mg powder?

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Semax lyophilized powder is typically reconstituted with bacteriostatic water or sterile water. Add 1-2ml of solvent per 30mg vial, introducing the liquid slowly down the inner wall without direct injection onto the powder. Gently swirl until dissolved so do not shake or vortex. Store the reconstituted solution refrigerated at 2-8°C, protected from light and avoid freeze thaw cycles. Do not freeze reconstituted solution. Full protocol is in the Reconstitution tab above.

What is the purity of this Semax peptide?

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Our Semax 30mg is manufactured to high purity, verified by independent third party HPLC analysis. A certificate of analysis (CoA) is available on request before or after purchase.

How should Semax powder be stored?

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Store lyophilized Semax powder at 2-8°C (36–46°F) in a cool, dark environment, protected from moisture and light to prevent degradation. Once reconstituted, keep the solution refrigerated and avoid repeated freeze thaw cycles. Do not freeze the reconstituted solution, as ice crystal formation will cause structural damage to the peptide.

What is the suggested research protocol timing for Semax?

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Research administration of Semax is typically conducted in the morning or on specific focus days. The standard cycle consists of 10-30 days ON followed by a mandatory 1-2 month OFF period for baseline observation. To observe long term cognitive effects, researchers may repeat the 10-30 day cycle every 3-6 months depending on specific research goals and environmental factors.

Do you ship internationally?

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Yes, we ship worldwide. Free shipping is included on qualifying orders. Cold chain packaging is used for all peptide orders to help maintain product integrity during transit.

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What is Semax and How Does It Relate to Cognitive Focus Research?

Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is a synthetic heptapeptide analogue of the adrenocorticotropic hormone fragment ACTH(4-10). Originally developed at the Institute of Molecular Genetics of the Russian Academy of Sciences in the 1980s, Semax is an extended analogue of the naturally occurring ACTH(4-7) tetrapeptide, with a Pro-Gly-Pro C terminal extension that significantly increases metabolic stability and blood brain barrier penetration compared to the parent molecule. Its CAS number is 80714-61-0 and its molecular weight is approximately 813.9 g/mol.

The primary research interest in Semax centres on its effects on cognitive function markers, including focus, memory retention, and mental clarity. Preclinical models have demonstrated upregulation of BDNF (Brain-Derived Neurotrophic Factor) in hippocampal tissue, a marker associated with synaptic plasticity, neurogenesis, and cognitive resilience. Separately, research has examined Semax’s interaction with dopaminergic and serotonergic neurotransmission with observed effects on monoamine turnover in cortical and limbic structures relevant to attention and executive function models.

Research protocols employing Semax typically apply a defined AM administration window on focused task days, within structured ON/OFF cycles of 10-30 days ON followed by a 1-2 month recovery period. This cycling approach creates clear baseline windows for measuring changes in cognitive performance markers and neurotrophic factor expression. For long term investigations, cycles may be repeated every 3-6 months to monitor cumulative neurological parameters.

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