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Ipamorelin 10mg | Sleep & Cellular Renewal Research Peptide

Ipamorelin (pentapeptide) is lyophilized selective growth hormone secretagogue used in research on sleep architecture, longevity markers and cellular renewal pathways.

Original price was: $120.00.Current price is: $100.00.

Suggested protocol

Timing: Night
Cycle: 20-30 days ON / 3-6 months OFF
Goal: Longevity, sleep, cellular renewal

High
Purity

CoA
Available

Cold-Chain
Shipping

Secure
Ordering

Ipamorelin is a synthetic pentapeptide and a selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS-R1a). It was the first growth hormone releasing peptide (GHRP) receptor agonist developed with selectivity comparable to growth hormone releasing hormone (GHRH) for stimulating GH release, notably without significantly affecting cortisol, ACTH or prolactin levels. This selective secretagogue is utilized in studies focused on longevity markers, sleep regulation mechanisms and cellular renewal pathways. BPeptide’s Ipamorelin 10mg is supplied as a lyophilized powder and is verified for identity and purity by independent third party analysis.

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Sleep Architecture Research

Used to study growth hormone pulsatility, which occurs predominantly during deep, slow wave sleep and its relationship to sleep regulation mechanisms.

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Cellular Renewal Pathways

Researched for downstream growth hormone effects on cellular regeneration markers and systemic tissue repair processes.

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Selective GHS-R1a Activation

Highly selective for GH secretion, distinguishing it from earlier generation GHRPs that also elevate cortisol and prolactin.

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Longevity Marker Tracking

Applied in longitudinal research protocols observing restorative biological cycles relevant to longevity and aging research.

Product Name

Ipamorelin (NNC 26-0161)

CAS Number

170851-70-4

Sequence

Aib-His-D-2-Nal-D-Phe-Lys-NH₂

Molecular Formula

C₃₈H₄₉N₉O₅

Molecular Weight

~711.85 g/mol

Quantity

10mg lyophilized powder

SKU

LPA10

Appearance

White to off-white lyophilized powder

Solubility

Soluble in sterile water and buffered aqueous solutions

Storage (lyophilized)

2–8°C, cool and dark, protected from light

Certificate of Analysis

Available on request

Category

Recovery & Gut Health

Intended Use

In vitro / laboratory research only

Standard Reconstitution Protocol

Allow the vial to reach room temperature before opening.
Wipe the rubber stopper with 70% isopropyl alcohol.
Using a sterile syringe, add 1.0–2.0ml of bacteriostatic or sterile water slowly down the inner wall of the vial so do not inject directly onto the powder.
Gently swirl until fully dissolved. Do not shake or vortex because this can denature the molecule.
Label the vial with date of reconstitution.
Store refrigerated to prevent ice crystal damage; avoid repeated freeze-thaw cycles.

Reconstitution solvent	Bacteriostatic water (preferred) or sterile water
Recommended volume	1.0-2.0ml per 10mg vial
Storage after reconstitution	2-8°C, in dark, upright
Freeze-thaw cycles	Avoid; do not freeze reconstituted solution
Suggested cycle	20-30 days ON, 3-6 months OFF
Maintenance cycle	May be repeated twice annually for longitudinal tracking

What is Ipamorelin used for in research?

Ipamorelin is a synthetic pentapeptide that acts as a selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS-R1a). In research, it is used to study growth hormone release mechanisms, sleep architecture (since growth hormone pulses occur predominantly during deep sleep) and downstream markers of cellular renewal and tissue repair, without significantly affecting cortisol, ACTH or prolactin levels.

How do you reconstitute Ipamorelin 10mg powder?

For research use, Ipamorelin lyophilized powder is typically reconstituted with bacteriostatic water or sterile water. A common approach is to add 1-2ml of solvent per 10mg vial. Store the reconstituted solution refrigerated at 2-8°C and avoid freeze thaw cycles. Full protocol is in the Reconstitution tab above.

What is the purity of this Ipamorelin peptide?

Our Ipamorelin 10mg is manufactured to high purity, verified by independent third party HPLC analysis. A certificate of analysis (CoA) is available on request before or after purchase.

How should Ipamorelin powder be stored?

Store lyophilized Ipamorelin powder at 2-8°C in cool, dark conditions, protected from light. Once reconstituted, peptides must be kept refrigerated to preserve structural integrity and prevent ice crystal damage. Avoid repeated freeze-thaw cycles.

What is the suggested research protocol timing?

A commonly referenced research protocol is conducted during night time laboratory sessions, aligning with the natural timing of growth hormone pulses during deep sleep. The typical cycle consists of 20-30 days ON, followed by a mandatory 3-6 month OFF period to observe long term physiological shifts. For long term age related research, the cycle may be repeated twice annually to monitor sustained impacts on sleep architecture and cellular regeneration markers.

Do you ship internationally?

Yes, we ship worldwide. Free shipping is included on qualifying orders. Cold chain packaging is used for all peptide orders to help maintain product integrity during transit.

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What is Ipamorelin and Why Is It Studied for Sleep and Cellular Renewal?

Ipamorelin is a synthetic pentapeptide with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂, derived from the earlier growth hormone releasing peptide GHRP-1. It functions as a selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS-R1a), and was the first compound in its class developed with selectivity for stimulating growth hormone (GH) release comparable to growth hormone-releasing hormone (GHRH) itself.

A key distinguishing feature in the published pharmacology is that Ipamorelin significantly increases plasma growth hormone levels in both animal and human research models without meaningfully elevating cortisol, ACTH, prolactin, FSH or LH, a selectivity profile that sets it apart from earlier growth hormone releasing peptides such as GHRP-2 and GHRP-6. Because growth hormone is released in pulsatile bursts that occur predominantly during deep, slow wave sleep, Ipamorelin is frequently used as a research tool to investigate the relationship between GH secretagogue activity and sleep architecture.

Downstream of growth hormone release, researchers also study Ipamorelin in the context of cellular renewal and tissue repair pathways, since GH and its mediator IGF-1 are established regulators of protein synthesis, cell turnover and recovery processes. Longitudinal research protocols often track sleep quality markers and tissue regeneration indicators across defined cycling periods to observe sustained effects relevant to longevity research.