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PT-141 10mg | Mitochondrial Health & Cellular Repair Research Peptide

Bremelanotide (PT-141) is lyophilized cyclic heptapeptide used as a melanocortin receptor tool compound, studied here for downstream cellular repair and mitochondrial health tracking.

Original price was: $120.00.Current price is: $100.00.

Suggested protocol

Timing: Morning
Cycle: 4-8 weeks ON / 4 week OFF
Goal: Mitochondrial health, cellular repair

High
Purity

CoA
Available

Cold-Chain
Shipping

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Ordering

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide derived from alpha melanocyte stimulating hormone (alpha MSH). It is widely used as a non selective melanocortin receptor tool compound, with documented binding activity across the MC1R, MC3R, MC4R and MC5R subtypes. This listing is used in laboratory investigations into mitochondrial health and cellular repair, with research focus on melanocortin receptor activation and its secondary, downstream impacts on systemic tissue recovery markers. BPeptide’s PT-141 10mg is supplied as a lyophilized powder and is verified for identity and purity by independent third party analysis.

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Cellular Repair Tracking

Studied for downstream signaling effects relevant to tissue recovery and cellular repair markers following melanocortin receptor activation.

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Mitochondrial Health Research

Used in protocols tracking mitochondrial efficiency and tissue integrity markers across extended observation cycles.

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Melanocortin Receptor Activation

Non selective agonist activity across MC1R, MC3R, MC4R and MC5R, well characterized in published receptor pharmacology literature.

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Stable Cyclic Structure

The cyclic lactam architecture improves resistance to enzymatic degradation, supporting reproducible in vitro assay conditions.

Product Name

PT-141 (Bremelanotide)

CAS Number

189691-06-3

Sequence

Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH

Molecular Formula

C₅₀H₆₈N₁₄O₁₀

Molecular Weight

~1025.2 g/mol

Quantity

10mg lyophilized powder

SKU

PT-141-10

Appearance

White to off-white lyophilized powder

Solubility

Water-soluble at research-relevant concentrations

Storage (lyophilized)

2–8°C, cool and dark, protected from moisture and light

Certificate of Analysis

Available on request

Category

Recovery & Gut Health

Intended Use

In vitro / laboratory research only

Standard Reconstitution Protocol

Allow the vial to reach room temperature before opening.
Wipe the rubber stopper with 70% isopropyl alcohol.
Using a sterile syringe, add 1.0-2.0ml of bacteriostatic or sterile water slowly down the inner wall of the vial so do not inject directly onto the powder.
Gently swirl until fully dissolved. Do not shake or vortex because this can denature the molecule.
Label the vial with date of reconstitution.
Store refrigerated, protected from light and avoid repeated freeze thaw cycles.

Reconstitution solvent	Bacteriostatic water (preferred) or sterile water
Recommended volume	1.0-2.0ml per 10mg vial
Storage after reconstitution	2-8°C, in dark, upright
Freeze thaw cycles	Avoid; do not freeze reconstituted solution
Suggested cycle	4-8 weeks ON, 4 week OFF
Maintenance cycle	Repeat periodically for longitudinal tracking

What is PT-141 used for in research?

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide derived from alpha MSH, studied primarily as a non selective agonist of melanocortin receptors (MC1R, MC3R, MC4R, MC5R). In this listing it is positioned for research into mitochondrial health and cellular repair signaling, examining secondary downstream effects of melanocortin receptor activation on tissue recovery markers.

How do you reconstitute PT-141 10mg powder?

For research use, PT-141 lyophilized powder is typically reconstituted with bacteriostatic water or sterile water. A common approach is to add 1-2ml of solvent per 10mg vial. Store the reconstituted solution refrigerated at 2-8°C, protected from light and avoid freeze thaw cycles. Full protocol is in the Reconstitution tab above.

What is the purity of this PT-141 peptide?

Our PT-141 10mg is manufactured to high purity, verified by independent third party HPLC analysis. A certificate of analysis (CoA) is available on request before or after purchase.

How should PT-141 powder be stored?

Store lyophilized PT-141 powder at 2-8°C in a cool, dark environment, protected from moisture and light to prevent degradation. Once reconstituted, keep the solution refrigerated and avoid repeated freeze thaw cycles.

What is the suggested research protocol timing?

A commonly referenced research protocol uses morning laboratory sessions for administration, with a standard cycle of 4-8 weeks ON followed by a mandatory 4 week OFF period to observe physiological stabilization. For longitudinal studies, the cycle can be repeated periodically to monitor sustained mitochondrial efficiency and tissue integrity markers.

Do you ship internationally?

Yes, we ship worldwide. Free shipping is included on qualifying orders. Cold chain packaging is used for all peptide orders to help maintain product integrity during transit.

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What is PT-141 and How Does It Relate to Cellular Repair Research?

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide structurally derived from alpha melanocyte stimulating hormone (alpha MSH), built around a lactam-bridged ring that gives it improved resistance to enzymatic degradation compared with linear peptide analogs. Its sequence, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH, is well characterized in the published pharmacology literature, where it is best known as a non selective agonist across the melanocortin receptor family (MC1R, MC3R, MC4R and MC5R).

The melanocortin system is most extensively studied for its role in central nervous system pathways, including its established research history around MC3R and MC4R signaling. Within that broader research landscape, this listing focuses on a narrower, less conventional application: examining how downstream signaling following melanocortin receptor activation may relate to cellular repair processes and mitochondrial efficiency. Researchers exploring this angle typically track tissue integrity markers across defined administration cycles, looking for secondary or indirect effects rather than a primary, well established mitochondrial mechanism.

Because PT-141’s receptor pharmacology is thoroughly documented elsewhere, it serves as a structurally stable, reproducible tool compound for laboratories designing exploratory studies into these secondary research questions. As with any tool compound applied outside its most established research context, results should be interpreted alongside the wider melanocortin receptor literature.