GHK-Cu 50mg | Skin Repair & Collagen Support Research Peptide

GHK-Cu (Copper Tripeptide-1) is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine (GHK). It was first isolated from human plasma in 1973 by biochemist Loren Pickart, and is also found naturally in saliva and urine. Plasma levels of GHK-Cu decline substantially with age, dropping from roughly 200 ng/ml at age 20 to around 80 ng/ml by age 60, a finding that has driven much of the interest in its tissue remodeling properties.

The GHK tripeptide has a strong binding affinity for copper(II) ions and the resulting GHK-Cu(II) complex serves two principal roles documented in the literature: as an anti inflammatory agent that protects tissue from oxidative damage following injury and as an activator of tissue remodeling during wound healing. During the wound healing process, GHK-Cu acts as a chemoattractant for inflammatory and endothelial cells and has been shown to increase messenger RNA production for collagen, elastin, proteoglycans and glycosaminoglycans in skin fibroblasts.

Beyond its role in collagen synthesis, published research has also examined GHK-Cu’s ability to stimulate growth of blood vessels and neurons, modulate the expression of a large number of human genes, and influence hair related biological pathways. Animal studies have demonstrated its wound healing activity through multiple mechanisms, including improved wound contraction, increased antioxidant enzyme activity and stimulated blood vessel growth.